Noujaim Laboratory

Dr. Noujaim obtained his PhD in Pharmacology from the SUNY Upstate Medical University in 2007. Subsequently, he completed his postdoctoral training at the University of Michigan (2008-2012), in the Laboratory of Dr. Jose Jalife.

Dr. Noujaim’s research focuses on the study of cardiac fibrillation mechanisms. Specifically, he is interested in the role that inward rectifiers play in atrial fibrillation (AF).

AF is the most prevalent arrhythmia in the clinic and a major cause of stroke. Pharmacological treatment of AF is inadequate. This is in part due to the relatively poor understanding of AF mechanisms and of the structural and molecular bases of drug-ion channel interactions.

The Noujaim laboratory uses technological, and conceptual advances from the fields of structural biology and ion channel trafficking in order to explore the electrophysiological details of the contribution of inward rectifiers, and specifically the acetylcholine sensitive potassium current (IKACh) to arrhythmogenesis in the atria. The laboratory also studies functional and trafficking aspects of drug-ion channels interactions.

Research Administrator: Dionne Bradford