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Molecular Cardiology Research Institute
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2009 Publications

Zhou J, Zhu Y, Cheng M, Dinesh D, Thorne T, Poh KK, Liu D, Botros C, Tang YL, Reisdorph N, Kishore R, Losordo DW, Qin G.  Regulation of vascular contractility and blood pressure by the E2F2 transcription factor.  Circulation 2009; 120(13):1213-1221.  PubMed Abstract

 

Zhang Y, Naggar JC, Welzig CM, Beasley D, Moulton KS, Park HJ, Galper JB.  Simvastatin inhibits angiotensin II-Induced abdominal aortic aneurysm formation in apolipoprotein E-knockout mice. possible role of ERK.  Arteriosclerosis Thrombosis, and Vascular Biology 2009; 29(11):1764-1771.   PubMed Abstract

 

Davis BD, Hata A.  Regulation of MicroRNA Biogenesis: A miRiad of mechanisms.  Cell Communication and Signaling 2009; 7:18.  PubMed Abstract

 

Mohaupt MG, Karas RH, Babiychuk EB, Sanchez-Freire V, Monastyrskaya K, Iyer L, Hoppeler H, Breil F, Draeger A.  Association between statin-associated myopathy and skeletal muscle damage.  Canadian Medical Association Journal 2009; 181(1-2):E-11-E18.  PubMed Abstract

 

Choi C, Fortin JP, McCarthy EV, Oksman L, Kopin AS, Nitabach MN.  Cellular dissection of circadian peptide signals with genetically encoded membrane-tethered ligands.  Current Biology 2009; 19(14):1167-1175.  PubMed Abstract

 

Abd-El-Barr MM, Pennesi ME, Saszik SM, Barrow AJ, Lem J, Bramblett DE, Paul DL, Frishman LJ, Wu SM.  Genetic dissection of rod and cone pathways in the dark-adapted mouse retina.  Journal of Neurophysiology 2009; 102(3):1945-1955.   PubMed Abstract

 

Vitale C, Mendelsohn ME, Rosano GM.  Gender differences in the cardiovascular effect of sex hormones.  Nature Reviews Cardiology 2009; 6(8):532-542.   PubMed Abstract

 

Han SY, Beinborn M, Ahn JM.  Facile synthesis of glucagon-like peptide-1 (GLP-1) mimetics. In: Advances in Experimental Medicine and Biology; Peptides for Youth; Susan Del Valle, Emanuel Escher and William D. Lubell (eds.), Springer New York 2009; 611:119-120.  PubMed Abstract

 

Ahn JM, Han SY, Murage E, Beinborn M.  Rational design of peptidomimetics for class B GPCRs: potent non-peptide GLP-1 receptor agonists. In: Advances in Experimental Medicine and Biology; Peptides for Youth; Susan Del Valle, Emanuel Escher and William D. Lubell (eds.), Springer New York 2009; 611:125-126.  PubMed Abstract

 

Murage E, Beinborn M, Ahn JM.  Seeking for alpha-helical propensity in a receptor-bound conformation of glucagon-like peptide-1. In: Advances in Experimental Medicine and Biology; Peptides for Youth; Susan Del Valle, Emanuel Escher and William D. Lubell (eds.), Springer New York 2009; 611:289-290.  PubMed Abstract

 

Dean J, Plante J, Huggins GS, Snyder RO, Aikawa R.  Role of CREB in recombinant adeno-associated virus-mediated transduction of heart muscle cells.  Human Gene Therapy 2009; 20(9):1005-1012.   PubMed Abstract

 

Patel AR, Hui H, Kuvin JT, Pandian NG, Karas RH.  Modestly overweight women have vascular endothelial dysfunction.  Clinical Cardiology 2009; 32(5):269-273.  PubMed Abstract

 

Park HJ, Zhang Y, Du C, Welzig CM, Madias C, Aronovitz MJ, Georgescu SP, Naggar I, Wang B, Kim YB, Blaustein RO, Karas RH, Liao R, Mathews CE, Galper JB.  Role of SREBP-1 in the Development of Parasympathetic Dysfunction in the Hearts of Type 1 Diabetic Akita Mice.  Circulation Research 2009; 105(3):278-294.  PubMed Abstract

 

Fortin JP, Zhu Y, Choi C, Beinborn M, Nitabach MN, Kopin AS.  Membrane-tethered ligands are effective probes for exploring class B1 G protein-coupled receptor function.  Proceedings of the National Academy of Sciences, USA 2009; 106(19):8049-8054  PubMed Abstract

 

Abraham J, Mudd JO, Kapur N, Klein K, Champion HC, Wittstein IS.  Stress cardiomyopathy after intravenous administration of catecholamines and beta-receptor agonists.  Journal of the American College of Cardiology 2009; 53(15):1320-1325.  PubMed Abstract

 

Park PS, Sapra KT, Jastrzebska B, Maeda T, Maeda A, Pulawski W, Kono M, Lem J, Crouch RK, Filipek S, Müller DJ, Palczewski K.  Modulation of molecular interactions and function by rhodopsin palmitylation.  Biochemistry 2009; 48(20):4294-4304.   PubMed Abstract

 

Gupta A, Hou R, Liu L, Hiroyasu S, Hadix JA, Huggins GS, Sibinga NE.  Daxx inhibits muscle differentiation by repressing E2A-mediated transcription.  Journal of Cellular Biochemistry 2009; 107(3):438-447.   PubMed Abstract

 

Aicher A, Heeschen C, Feil S, Hofmann F, Mendelsohn ME, Feil R, Dimmeler S.  cGMP-dependent protein kinase I is crucial for angiogenesis and postnatal vasculogenesis.  PLoS One 2009; 4(3):e4879.   PubMed Abstract

 

Schultz K, Murthy V, Tatro JB, Beasley D.  Prolyl hydroxylase 2 deficiency limits proliferation of vascular smooth muscle cells by HIF-1{alpha}-dependent mechanisms.  American Journal of Physiology - Lung Cellular and Molecular Physiology 2009; 296(6):L921-L927.  PubMed Abstract

 

Neuman NA, Ma S, Schnitzler GR, Zhu Y, Lagna G, Hata A.  The four-and-a-half lim domain protein 2 regulates vascular smooth muscle phenotype and vascular tone.  Journal of Biological Chemistry 2009; 284(19):13202-13212.   PubMed Abstract

 

Patten RD, Hall-Porter MR.  Small animal models of heart failure: Development of novel therapies, past and present.  Circulation: Heart Failure 2009; 2(2):138-144.  PubMed Abstract

 

Alsheikh-AA, Karas RH.  The relationship of statins to rhabdomyolysis, malignancy, and hepatic toxicity: evidence from clinical trials.  Current Atherosclerosis Report 2009;11(2):100-104.  PubMed Abstract

 

Heffernan KS, Karas RH, Kuvin JT, Jae SY, Vieira VJ, Fernhall B.  Carotid artery stiffness, high-density lipoprotein cholesterol and inflammation in men with pre-hypertension.  Journal of Human Hypertension 2009; 23(9):590-596.   PubMed Abstract

 

Peter I, Hedgepeth AK, Huggins GS, Housman DE, Mendelsohn ME, Vita JA, Vasan RS, Levy D, Benjamin EJ, Mitchell GM.  Association between arterial stiffness and variations in estrogen-related genes.  Journal of Human Hypertension 2009; 23(10):636-644  PubMed Abstract

 

Wen XH, Shen L, Brush RS, Michaud N, Al-Ubaidi MR, Gurevich VV, Hamm HE, Lem J, Dibenedetto E, Anderson RE, Makino CL.  Overexpression of rhodopsin alters the structure and photoresponse of rod photoreceptors.  Biophysical Journal 2009;96(3):939-950.  PubMed Abstract

 

Patlolla V, Patten RD, Denofrio D, Konstam MA, Krishnamani R.  The effect of ventricular assist devices on post-transplant mortality an analysis of the United network for organ sharing thoracic registry.  Journal of American College of Cardiology 2009;53(3):264-271.  PubMed Abstract

 

Sweet TB, Cox DH.  Measuring the influence of the BKca β1 subunit on Ca²+ binding to the BKca channel.  Journal of General Physiology 2009;133(2):139-150.  PubMed Abstract

 

Wang Y, Zheng XR, Riddick N, Bryden M, Baur W, Zhang X, Surks HK.  ROCK isoform regulation of myosin phosphatase and contractility in vascular smooth muscle cell.  Circulation Research 2009;104(4):531-540.  PubMed Abstract

 

Takimoto E, Koitabashi N, Hsu S, Ketner EA, Zhang M, Nagayama T, Bedja D, Gabrielson KL, Blanton R, Siderovski DP, Mendelsohn ME, Kass DA.  Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice.  Journal of Clinical Investigation 2009;119(2):408-420.  PubMed Abstract

 

Kelley-Hedgepeth A, Peter I, Montefusco MC, Levy D, Benjamin EJ, Vasan RS, Mendelsohn ME, Housman D, Huggins GS, Mitchell GF.  The KCNMB1 E65K variant is associated with reduced central pulse pressure in the community-based Framingham Offspring Cohort.  Journal of Hypertension 2009;27(1):55-60.  PubMed Abstract

 

Caprio M, Mammi C, Jaffe IZ, Zennaro MC, Aversa A, Mendelsohn ME, Fabbri A, Rosano G.  The mineralocorticoid receptor in endothelial physiology and disease: Novel concepts in the understanding of erectile dysfuction.  Current Pharmaceutica Design 2008;14(35):3749-3757.  PubMed Abstract

 

Kyriakis JM.  Thinking outside the box about Ras.  Journal of Biological Chemistry 2008; 284(17):10993-10994.   PubMed Abstract

 

Davis BN, Hilyard AC, Nguyen PN, Lagna G, Hata A.  Induction of microrna-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype.  Journal of Biological Chemistry 2008;284(6):3728-3738. PubMed Abstract

 

Donaldson C, Eder S, Baker C, Aronovitz MJ, Weiss AD, Hall-Porter M, Wang F, Ackerman A, Karas RH, Molkentin JD, Patten RD.  Estrogen attenuates left ventricular and cardiomyocyte hypertrophy by an estrogen receptor-dependent pathway that increases calcineurin degradation.  Circulation Research 2008;104(2):265-275.  PubMed Abstract

 

Brieke A, Krishnamani R, Rocha MJ, Li W, Patten RD, Konstam MA, Patel AR, Udelson JE, Denofrio D.  Influence of donor cocaine use on outcome after cardiac transplantation: Analysis of the united network for organ sharing thoracic registry.  Journal of Heart and Lung Transplantation 2008;27(12):1350-1352.  PubMed Abstract