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Guang-Rong Wang, M.D.

  Research Associate
Molecular Cardiology Research Center

Tufts Medical Center

800 Washington Street, Box 080

Boston, MA 02111

    617-636-8236

Guang-Rong Wang




Guang-Rong Wang received his M.D. degree from the Shanghai Medical University and was a Research Assistant Professor/Physician-in-charge in China. His research in China consisted of the work on enterotoxigenic E.coli, Hepatitis B virus, catecholamines and other topics. For this work, he earned a number of awards, including a highly prestigious national one. From 1988 to 1994, he was a visiting scientist working with Dr. Edward B.Goldberg on the assembly and physiology of bacteriophage T4 in the Department of Molecular Biology and Microbiology, Tufts University School of Medicine. He arrived at Dr. Michael E. Mendelsohn's Laboratory in 1994. Since then, he has been a Research Associate working on the mechanism of platelet inhibition by NO, including the thrombin and thromboxane receptors and cGMP-dependent protein kinase as well its substrates.
Key Publications

Benka Mary Lynn, Lee M, Wang GR, Buckman S, Burlacu A, Cole L, Depina A, Dias P, Granger A, Grant B, Hayward-Lester A, Karki S, Mann S, Marcu O, Nussenzweig A, Piepenhagen P, Raje M, Roegiers F, Rybak S, Salic A, Smith-Hall J, Waters J,  Yamamoto N,  Yanowitz J,  Yeow K, Busa WB, Mendelsohn ME. (1995) The thrombin receptor in human platelets is coupled to a GTP binding protein of the Gaq family, FEBS Letters 363: 49-52.  PubMed Abstract

 

Wang, G. R., Vianelli, A., and Goldberg, E.B. 2000. Bacteriophage T4 Self-Assembly: In Vitro reconstitution of Recombinant gp2 into Infectious Phage. J. Bacteriol. 182: 672-679.  PubMed Abstract

 

Vianelli, A., Wang, G. R., Gingery, M., Duda, R. L., Eiserling, F. A., and Goldberg, E.B. 2000. Bacteriophage T4 Self-Assembly: Localization of gp3 and Its Role in Determining Tail Length. J. Bacteriol. 182: 680-688.  PubMed Abstract

 

Wang, G. R., Zhu, Y., Halushka, P. V., Lincoln, T. M., and Mendelsohn, M. E. 1998. Mechanism of platelet Inhibition by Nitro Oxide: In Vivo Phosphorylation of Thromboxane receptor by Cyclic GMP-dependent Protein Kinase. Proc. Natl. Acad. Sci. USA. 95: 4888-4983.  PubMed Abstract