Selected MCRI Publications

Mendelsohn ME, Karas RH. Rapid progress for non-nuclear estrogen receptor signaling.  Journal of Clinical Investigation 2010; 120(7):2277-2279.  PubMed

Zhang Y, Naggar JC, Welzig CM, Beasley D, Moulton KS, Park HJ, Galper JB.  Simvastatin inhibits angiotensin II-Induced abdominal aortic aneurysm formation in apolipoprotein E-knockout mice. Possible role of ERK.  Arteriosclerosis Thrombosis, and Vascular Biology 2009; 29(11):1764-1771.  PubMed

Park HJ, Zhang Y, Du C, Welzig CM, Madias C, Aronovitz MJ, Georgescu SP, Naggar I, Wang B, Kim YB, Blaustein RO, Karas RH, Liao R, Mathews CE, Galper JB.  Role of SREBP-1 in the Development of Parasympathetic Dysfunction in the Hearts of Type 1 Diabetic Akita Mice.  Circulation Research 2009; 105(3):278-294.  PubMed Abstract

Fortin JP, Zhu Y, Choi C, Beinborn M, Nitabach MN, Kopin AS.  Membrane-tethered ligands are effective probes for exploring class B1 G protein-coupled receptor function.  Proceedings of the National Academy of Sciences, USA 2009; 106(19):8049-8054   PubMed Abstract

Schultz K, Murthy V, Tatro JB, Beasley D.  Prolyl hydroxylase 2 deficiency limits proliferation of vascular smooth muscle cells by HIF-1{alpha}-dependent mechanisms.  American Journal of Physiology - Lung Cellular and Molecular Physiology 2009; 296(6):L921-L927.   PubMed Abstract

Neuman NA, Ma S, Schnitzler GR, Zhu Y, Lagna G, Hata A.  The four-and-a-half lim domain protein 2 regulates vascular smooth muscle phenotype and vascular tone.  Journal of Biological Chemistry 2009; 284(19):13202-13212.   PubMed Abstract

Zhong J, Gavrilescu LC, Molnár A, Murray L, Garafalo S, Kehrl JH, Simon AR, Van Etten RA, Kyriakis JM.  GCK is essential to systemic inflammation and pattern recognition receptor signaling to JNK and p38.  Proceedings of the National Academy of Sciences, USA 2009;106(11):4372-4377.  PubMed Abstract

Takimoto E, Koitabashi N, Hsu S, Ketner EA, Zhang M, Nagayama T, Bedja D, Gabrielson KL, Blanton R, Siderovski DP, Mendelsohn ME, Kass DA.  Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice.  Journal of Clinical Investigation 2009;119(2):408-420.  PubMed Abstract

Davis BN, Hilyard AC, Lagna G, Hata A.  SMAD proteins control DROSHA-mediated microRNA maturation.  Nature 2008; 454(7200):56-61.  PubMed Abstract

Kerkela R, Kockeritz L, Macaulay K, Zhou J, Doble BW, Beahm C, Greytak S, Woulfe K, Trivedi CM, Woodgett JR, Epstein JA, Force T, Huggins GS.  Deletion of GSK-3β in Mice Leads to Hypertrophic Cardiomyopathy Secondary to Cardiomyoblast Hyperproliferation.  Journal of Clinical Investigation 2008;118(11):3609-3618.  PubMed Abstract

Caprio M, Newfell BG, la Sala A, Baur W, Fabbri A, Rosano G, Mendelsohn ME, Jaffe IZ.  Functional mineralocorticoid receptors in human vascular endothelial cells regulate intercellular adhesion molecule-1 expression and promote leukocyte adhesion.  Circulation Research 2008;102(11):1359-1367.  PubMed Abstract

Michael S, Surks HK, Wang Y, Zhu Y, Blanton R, Jamnongit M, Aronovitz M, Baur W, Ohtani K, Wilkerson MK, Bonev AD, Nelson MT, Karas RH, Mendelsohn ME.  High blood pressure arising from a defect in vascular function.  Proceedings of the National Academy of Sciences, USA 2008;105(18):6702-6707.  PubMed Abstract

Park HJ, Georgescu SP, Du C, Madias C, Aronovitz MJ, Welzig CM, Wang B, Begley U, Zhang Y, Blaustein RO, Patten RD, Karas RH, Van Tol HH, Osborne TF, Shimano H, Liao R, Link MS, Galper JB.  Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP.  Journal of Clinical Investigation 2008;118(1):259-271.  PubMed Abstract

Brill E, Malanson KM, Radu RA, Boukharov, NV, Wang Z, Chung H-Y, Lloyd MB, Bok D, Travis GH, Obin M, Lem J.  A novel form of transducin-dependent retinal degeneration: Accelerated retinal degeneration in the absence of rod transducin.  Investigative Ophthalmology & Visual Science 2007;48(12):5445-5453.  PubMed Abstract

Mendelsohn ME, Karas RH.  HRT and the Young at Heart.  New England Journal of Medicine 2007; 356(25):2639-2641.  PubMed Abstract

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